RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf01037 |
| Gene Symbol | I15RA | |
| Gene Description | Interleukin-15 receptor subunit alpha (IL-15 receptor subunit alpha) (IL-15R-alpha) (IL-15RA) (CD antigen CD215) [Cleaved into: Soluble interleukin-15 receptor subunit alpha (sIL-15 receptor subunit alpha) (sIL-15R-alpha) (sIL-15RA)] | |
| Gene Name in Paper | IL15RA | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000379971 ENST00000379977 ENST00000397250 ENST00000397255 ENST00000525219 ENST00000528354 ENST00000530685 | |
| UniProt ID | Q13261 | |
| Entrez Gene ID | 3601 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Adeno-associated virus |
| Virus Abbreviation | AAV | |
| Taxonomy | View | |
| Results | Phenotype | Increased transduction |
| Hits Number* | 1483 | |
| Confirmed Hits Number | 515 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | cell-based |
| BioModel Description | HEK293 and HeLa cells | |
| Confirmatory Screen Description | Immunofluorescence | |
| Primary Screen Description# | log 2 Luc/AB ratio >2 | |
| Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
| References | Pubmed ID | 26305933 |