RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf00994 |
| Gene Symbol | TAP1 | |
| Gene Description | Antigen peptide transporter 1 (APT1) (ATP-binding cassette sub-family B member 2) (Peptide supply factor 1) (Peptide transporter PSF1) (PSF-1) (Peptide transporter TAP1) (Peptide transporter involved in antigen processing 1) (Really interesting new gene 4 protein) | |
| Gene Name in Paper | TAP1 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000354258 ENST00000383235 ENST00000414467 ENST00000418205 ENST00000424897 ENST00000439781 ENST00000440894 | |
| UniProt ID | Q03518 | |
| Entrez Gene ID | 6890 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Adeno-associated virus |
| Virus Abbreviation | AAV | |
| Taxonomy | View | |
| Results | Phenotype | Increased transduction |
| Hits Number* | 1483 | |
| Confirmed Hits Number | 515 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | cell-based |
| BioModel Description | HEK293 and HeLa cells | |
| Confirmatory Screen Description | Immunofluorescence | |
| Primary Screen Description# | log 2 Luc/AB ratio >2 | |
| Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
| References | Pubmed ID | 26305933 |