RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf00967 |
Gene Symbol | DEN5B | |
Gene Description | DENN domain-containing protein 5B (Rab6IP1-like protein) | |
Gene Name in Paper | MGC24039 | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000354285 ENST00000389082 | |
UniProt ID | Q6ZUT9 | |
Entrez Gene ID | 160518 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Adeno-associated virus |
Virus Abbreviation | AAV | |
Taxonomy | View | |
Results | Phenotype | Increased transduction |
Hits Number* | 1483 | |
Confirmed Hits Number | 515 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | cell-based |
BioModel Description | HEK293 and HeLa cells | |
Confirmatory Screen Description | Immunofluorescence | |
Primary Screen Description# | log 2 Luc/AB ratio >2 | |
Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
References | Pubmed ID | 26305933 |