RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf00920 |
Gene Symbol | PE2R3 | |
Gene Description | Prostaglandin E2 receptor EP3 subtype (PGE receptor EP3 subtype) (PGE2 receptor EP3 subtype) (PGE2-R) (Prostanoid EP3 receptor) | |
Gene Name in Paper | PTGER3 | |
Group | Restriction Factor | |
Ensembl Gene ID | ENST00000306666 ENST00000351052 ENST00000356595 ENST00000370924 ENST00000370931 ENST00000460330 ENST00000479353 ENST00000628037 | |
UniProt ID | P43115 | |
Entrez Gene ID | 5733 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Adeno-associated virus |
Virus Abbreviation | AAV | |
Taxonomy | View | |
Results | Phenotype | Inhibited transduction |
Hits Number* | 1483 | |
Confirmed Hits Number | 968 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | cell-based |
BioModel Description | HEK293 and HeLa cells | |
Confirmatory Screen Description | Immunofluorescence | |
Primary Screen Description# | log 2 Luc/AB ratio >2 | |
Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
References | Pubmed ID | 26305933 |