Vhf00920 details

Gene vhfRNAi AccessionVhf00920
Gene SymbolPE2R3
Gene DescriptionProstaglandin E2 receptor EP3 subtype (PGE receptor EP3 subtype) (PGE2 receptor EP3 subtype) (PGE2-R) (Prostanoid EP3 receptor)
Gene Name in PaperPTGER3
GroupRestriction Factor
Ensembl Gene IDENST00000306666  ENST00000351052  ENST00000356595  ENST00000370924  ENST00000370931  ENST00000460330  ENST00000479353  ENST00000628037  
UniProt IDP43115
Entrez Gene ID5733
GOView
Host OrganismHomo sapiens
Virus Virus full nameAdeno-associated virus
Virus AbbreviationAAV 
TaxonomyView
Results PhenotypeInhibited transduction
Hits Number*1483
Confirmed Hits Number968 
ScoreNA
UnitNA
Methods Assay Type cell-based
BioModel DescriptionHEK293 and HeLa cells
Confirmatory Screen DescriptionImmunofluorescence
Primary Screen Description#log 2 Luc/AB ratio >2
Note/CommentHost restriction factors critical for in vivo AAV transduction
References Pubmed ID26305933
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)