Vhf00910 details

Gene vhfRNAi AccessionVhf00910
Gene SymbolBCAR1
Gene DescriptionBreast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (Cas scaffolding protein family member 1) (p130cas)
Gene Name in PaperBCAR1
GroupRestriction Factor
Ensembl Gene IDENST00000162330  ENST00000393420  ENST00000393422  ENST00000418647  ENST00000420641  ENST00000535626  ENST00000538440  ENST00000542031  
UniProt IDP56945
Entrez Gene ID9564
GOView
Host OrganismHomo sapiens
Virus Virus full nameAdeno-associated virus
Virus AbbreviationAAV 
TaxonomyView
Results PhenotypeInhibited transduction
Hits Number*1483
Confirmed Hits Number968 
ScoreNA
UnitNA
Methods Assay Type cell-based
BioModel DescriptionHEK293 and HeLa cells
Confirmatory Screen DescriptionImmunofluorescence
Primary Screen Description#log 2 Luc/AB ratio >2
Note/CommentHost restriction factors critical for in vivo AAV transduction
References Pubmed ID26305933
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)