RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf00881 |
Gene Symbol | ZN197 | |
Gene Description | Zinc finger protein 197 (Zinc finger protein with KRAB and SCAN domains 9) (ZnF20) (pVHL-associated KRAB domain-containing protein) | |
Gene Name in Paper | ZNF197 | |
Group | Restriction Factor | |
Ensembl Gene ID | ENST00000344387 ENST00000383744 ENST00000383745 ENST00000396058 ENST00000627517 ENST00000627752 ENST00000627845 ENST00000628172 | |
UniProt ID | O14709 | |
Entrez Gene ID | 10168 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Adeno-associated virus |
Virus Abbreviation | AAV | |
Taxonomy | View | |
Results | Phenotype | Inhibited transduction |
Hits Number* | 1483 | |
Confirmed Hits Number | 968 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | cell-based |
BioModel Description | HEK293 and HeLa cells | |
Confirmatory Screen Description | Immunofluorescence | |
Primary Screen Description# | log 2 Luc/AB ratio >2 | |
Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
References | Pubmed ID | 26305933 |