Vhf00857 details

Gene vhfRNAi AccessionVhf00857
Gene SymbolF149A
Gene DescriptionProtein FAM149A
Gene Name in PaperDKFZP564J102
GroupRestriction Factor
Ensembl Gene IDENST00000227065  ENST00000356371  ENST00000502970  ENST00000503432  ENST00000514153  
UniProt IDA5PLN7
Entrez Gene ID25854
GOView
Host OrganismHomo sapiens
Virus Virus full nameAdeno-associated virus
Virus AbbreviationAAV 
TaxonomyView
Results PhenotypeInhibited transduction
Hits Number*1483
Confirmed Hits Number968 
ScoreNA
UnitNA
Methods Assay Type cell-based
BioModel DescriptionHEK293 and HeLa cells
Confirmatory Screen DescriptionImmunofluorescence
Primary Screen Description#log 2 Luc/AB ratio >2
Note/CommentHost restriction factors critical for in vivo AAV transduction
References Pubmed ID26305933
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)