RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf00846 |
Gene Symbol | OR4D2 | |
Gene Description | Olfactory receptor 4D2 (B-lymphocyte membrane protein BC2009) (Olfactory receptor OR17-24) | |
Gene Name in Paper | OR4D2 | |
Group | Restriction Factor | |
Ensembl Gene ID | ENST00000545221 | |
UniProt ID | P58180 | |
Entrez Gene ID | 124538 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Adeno-associated virus |
Virus Abbreviation | AAV | |
Taxonomy | View | |
Results | Phenotype | Inhibited transduction |
Hits Number* | 1483 | |
Confirmed Hits Number | 968 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | cell-based |
BioModel Description | HEK293 and HeLa cells | |
Confirmatory Screen Description | Immunofluorescence | |
Primary Screen Description# | log 2 Luc/AB ratio >2 | |
Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
References | Pubmed ID | 26305933 |