Vhf00835 details

Gene vhfRNAi AccessionVhf00835
Gene SymbolCRERF
Gene DescriptionCREB3 regulatory factor (Luman recruitment factor) (LRF)
Gene Name in PaperLOC153222
GroupRestriction Factor
Ensembl Gene IDENST00000296953  ENST00000520420  ENST00000522692  
UniProt IDQ8IUR6
Entrez Gene ID153222
GOView
Host OrganismHomo sapiens
Virus Virus full nameAdeno-associated virus
Virus AbbreviationAAV 
TaxonomyView
Results PhenotypeInhibited transduction
Hits Number*1483
Confirmed Hits Number968 
ScoreNA
UnitNA
Methods Assay Type cell-based
BioModel DescriptionHEK293 and HeLa cells
Confirmatory Screen DescriptionImmunofluorescence
Primary Screen Description#log 2 Luc/AB ratio >2
Note/CommentHost restriction factors critical for in vivo AAV transduction
References Pubmed ID26305933
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)