RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf00817 |
| Gene Symbol | APC1 | |
| Gene Description | Anaphase-promoting complex subunit 1 (APC1) (Cyclosome subunit 1) (Mitotic checkpoint regulator) (Testis-specific gene 24 protein) | |
| Gene Name in Paper | ANAPC1 | |
| Group | Restriction Factor | |
| Ensembl Gene ID | ENST00000341068 | |
| UniProt ID | Q9H1A4 | |
| Entrez Gene ID | 64682 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Adeno-associated virus |
| Virus Abbreviation | AAV | |
| Taxonomy | View | |
| Results | Phenotype | Inhibited transduction |
| Hits Number* | 1483 | |
| Confirmed Hits Number | 968 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | cell-based |
| BioModel Description | HEK293 and HeLa cells | |
| Confirmatory Screen Description | Immunofluorescence | |
| Primary Screen Description# | log 2 Luc/AB ratio >2 | |
| Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
| References | Pubmed ID | 26305933 |