RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf00804 |
| Gene Symbol | GPN1 | |
| Gene Description | GPN-loop GTPase 1 (EC 3.6.5.-) (MBD2-interacting protein) (MBDin) (RNAPII-associated protein 4) (XPA-binding protein 1) | |
| Gene Name in Paper | XAB1 | |
| Group | Restriction Factor | |
| Ensembl Gene ID | ENST00000264718 ENST00000407583 ENST00000424214 ENST00000458167 ENST00000503738 ENST00000515877 ENST00000610189 ENST00000616939 | |
| UniProt ID | Q9HCN4 | |
| Entrez Gene ID | 11321 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Adeno-associated virus |
| Virus Abbreviation | AAV | |
| Taxonomy | View | |
| Results | Phenotype | Inhibited transduction |
| Hits Number* | 1483 | |
| Confirmed Hits Number | 968 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | cell-based |
| BioModel Description | HEK293 and HeLa cells | |
| Confirmatory Screen Description | Immunofluorescence | |
| Primary Screen Description# | log 2 Luc/AB ratio >2 | |
| Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
| References | Pubmed ID | 26305933 |