Vhf00796 details

Gene vhfRNAi AccessionVhf00796
Gene SymbolHNRPC
Gene DescriptionHeterogeneous nuclear ribonucleoproteins C1/C2 (hnRNP C1/C2)
Gene Name in PaperHNRPC
GroupRestriction Factor
Ensembl Gene IDENST00000420743  ENST00000430246  ENST00000553300  ENST00000554455  ENST00000554969  ENST00000555883  ENST00000556628  ENST00000556897  ENST00000557201  
UniProt IDP07910
Entrez Gene ID3183
GOView
Host OrganismHomo sapiens
Virus Virus full nameAdeno-associated virus
Virus AbbreviationAAV 
TaxonomyView
Results PhenotypeInhibited transduction
Hits Number*1483
Confirmed Hits Number968 
ScoreNA
UnitNA
Methods Assay Type cell-based
BioModel DescriptionHEK293 and HeLa cells
Confirmatory Screen DescriptionImmunofluorescence
Primary Screen Description#log 2 Luc/AB ratio >2
Note/CommentHost restriction factors critical for in vivo AAV transduction
References Pubmed ID26305933
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)