RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf00786 |
Gene Symbol | DUS15 | |
Gene Description | Dual specificity protein phosphatase 15 (EC 3.1.3.16) (EC 3.1.3.48) (VH1-related member Y) (Vaccinia virus VH1-related dual-specific protein phosphatase Y) | |
Gene Name in Paper | DUSP15 | |
Group | Restriction Factor | |
Ensembl Gene ID | ENST00000278979 ENST00000339738 ENST00000375966 ENST00000398083 ENST00000398084 ENST00000486996 | |
UniProt ID | Q9H1R2 | |
Entrez Gene ID | 128853 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Adeno-associated virus |
Virus Abbreviation | AAV | |
Taxonomy | View | |
Results | Phenotype | Inhibited transduction |
Hits Number* | 1483 | |
Confirmed Hits Number | 968 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | cell-based |
BioModel Description | HEK293 and HeLa cells | |
Confirmatory Screen Description | Immunofluorescence | |
Primary Screen Description# | log 2 Luc/AB ratio >2 | |
Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
References | Pubmed ID | 26305933 |