Vhf00777 details

Gene vhfRNAi AccessionVhf00777
Gene SymbolUCP5
Gene DescriptionBrain mitochondrial carrier protein 1 (BMCP-1) (Mitochondrial uncoupling protein 5) (UCP 5) (Solute carrier family 25 member 14)
Gene Name in PaperSLC25A14
GroupRestriction Factor
Ensembl Gene IDENST00000218197  ENST00000339231  ENST00000361980  ENST00000545805  ENST00000612248  
UniProt IDO95258
Entrez Gene ID9016
GOView
Host OrganismHomo sapiens
Virus Virus full nameAdeno-associated virus
Virus AbbreviationAAV 
TaxonomyView
Results PhenotypeInhibited transduction
Hits Number*1483
Confirmed Hits Number968 
ScoreNA
UnitNA
Methods Assay Type cell-based
BioModel DescriptionHEK293 and HeLa cells
Confirmatory Screen DescriptionImmunofluorescence
Primary Screen Description#log 2 Luc/AB ratio >2
Note/CommentHost restriction factors critical for in vivo AAV transduction
References Pubmed ID26305933
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)