RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf00748 |
| Gene Symbol | TRI40 | |
| Gene Description | Tripartite motif-containing protein 40 (Probable E3 NEDD8-protein ligase) (RING finger protein 35) | |
| Gene Name in Paper | TRIM40 | |
| Group | Restriction Factor | |
| Ensembl Gene ID | ENST00000307859 ENST00000376724 ENST00000383610 ENST00000396581 ENST00000400651 ENST00000421981 ENST00000429471 ENST00000433713 ENST00000434151 ENST00000436951 ENST00000437563 ENST00000547289 ENST00000549728 ENST00000552119 ENST00000616351 | |
| UniProt ID | Q6P9F5 | |
| Entrez Gene ID | 135644 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Adeno-associated virus |
| Virus Abbreviation | AAV | |
| Taxonomy | View | |
| Results | Phenotype | Inhibited transduction |
| Hits Number* | 1483 | |
| Confirmed Hits Number | 968 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | cell-based |
| BioModel Description | HEK293 and HeLa cells | |
| Confirmatory Screen Description | Immunofluorescence | |
| Primary Screen Description# | log 2 Luc/AB ratio >2 | |
| Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
| References | Pubmed ID | 26305933 |