RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf00740 |
Gene Symbol | TGON2 | |
Gene Description | Trans-Golgi network integral membrane protein 2 (TGN38 homolog) (TGN46) (TGN48) (Trans-Golgi network protein TGN51) | |
Gene Name in Paper | TGOLN2 | |
Group | Restriction Factor | |
Ensembl Gene ID | ENST00000377386 ENST00000398263 ENST00000409232 ENST00000444342 | |
UniProt ID | O43493 | |
Entrez Gene ID | 10618 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Adeno-associated virus |
Virus Abbreviation | AAV | |
Taxonomy | View | |
Results | Phenotype | Inhibited transduction |
Hits Number* | 1483 | |
Confirmed Hits Number | 968 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | cell-based |
BioModel Description | HEK293 and HeLa cells | |
Confirmatory Screen Description | Immunofluorescence | |
Primary Screen Description# | log 2 Luc/AB ratio >2 | |
Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
References | Pubmed ID | 26305933 |