RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf00733 |
Gene Symbol | DIDO1 | |
Gene Description | Death-inducer obliterator 1 (DIO-1) (hDido1) (Death-associated transcription factor 1) (DATF-1) | |
Gene Name in Paper | DATF1 | |
Group | Restriction Factor | |
Ensembl Gene ID | ENST00000266070 ENST00000354665 ENST00000370366 ENST00000370368 ENST00000370371 ENST00000395340 ENST00000395343 | |
UniProt ID | Q9BTC0 | |
Entrez Gene ID | 11083 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Adeno-associated virus |
Virus Abbreviation | AAV | |
Taxonomy | View | |
Results | Phenotype | Inhibited transduction |
Hits Number* | 1483 | |
Confirmed Hits Number | 968 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | cell-based |
BioModel Description | HEK293 and HeLa cells | |
Confirmatory Screen Description | Immunofluorescence | |
Primary Screen Description# | log 2 Luc/AB ratio >2 | |
Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
References | Pubmed ID | 26305933 |