Vhf00733 details

Gene vhfRNAi AccessionVhf00733
Gene SymbolDIDO1
Gene DescriptionDeath-inducer obliterator 1 (DIO-1) (hDido1) (Death-associated transcription factor 1) (DATF-1)
Gene Name in PaperDATF1
GroupRestriction Factor
Ensembl Gene IDENST00000266070  ENST00000354665  ENST00000370366  ENST00000370368  ENST00000370371  ENST00000395340  ENST00000395343  
UniProt IDQ9BTC0
Entrez Gene ID11083
GOView
Host OrganismHomo sapiens
Virus Virus full nameAdeno-associated virus
Virus AbbreviationAAV 
TaxonomyView
Results PhenotypeInhibited transduction
Hits Number*1483
Confirmed Hits Number968 
ScoreNA
UnitNA
Methods Assay Type cell-based
BioModel DescriptionHEK293 and HeLa cells
Confirmatory Screen DescriptionImmunofluorescence
Primary Screen Description#log 2 Luc/AB ratio >2
Note/CommentHost restriction factors critical for in vivo AAV transduction
References Pubmed ID26305933
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)