RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf00729 |
Gene Symbol | AT5G1 | |
Gene Description | ATP synthase F(0) complex subunit C1, mitochondrial (ATP synthase lipid-binding protein) (ATP synthase proteolipid P1) (ATP synthase proton-transporting mitochondrial F(0) complex subunit C1) (ATPase protein 9) (ATPase subunit c) | |
Gene Name in Paper | ATP5G1 | |
Group | Restriction Factor | |
Ensembl Gene ID | ENST00000355938 ENST00000393366 | |
UniProt ID | P05496 | |
Entrez Gene ID | 516 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Adeno-associated virus |
Virus Abbreviation | AAV | |
Taxonomy | View | |
Results | Phenotype | Inhibited transduction |
Hits Number* | 1483 | |
Confirmed Hits Number | 968 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | cell-based |
BioModel Description | HEK293 and HeLa cells | |
Confirmatory Screen Description | Immunofluorescence | |
Primary Screen Description# | log 2 Luc/AB ratio >2 | |
Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
References | Pubmed ID | 26305933 |