RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf00721 |
| Gene Symbol | PO5F1 | |
| Gene Description | POU domain, class 5, transcription factor 1 (Octamer-binding protein 3) (Oct-3) (Octamer-binding protein 4) (Oct-4) (Octamer-binding transcription factor 3) (OTF-3) | |
| Gene Name in Paper | POU5F1 | |
| Group | Restriction Factor | |
| Ensembl Gene ID | ENST00000259915 ENST00000376243 ENST00000383524 ENST00000412166 ENST00000419095 ENST00000429314 ENST00000429603 ENST00000433063 ENST00000433348 ENST00000434616 ENST00000437747 ENST00000451077 ENST00000454714 | |
| UniProt ID | Q01860 | |
| Entrez Gene ID | 5460 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Adeno-associated virus |
| Virus Abbreviation | AAV | |
| Taxonomy | View | |
| Results | Phenotype | Inhibited transduction |
| Hits Number* | 1483 | |
| Confirmed Hits Number | 968 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | cell-based |
| BioModel Description | HEK293 and HeLa cells | |
| Confirmatory Screen Description | Immunofluorescence | |
| Primary Screen Description# | log 2 Luc/AB ratio >2 | |
| Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
| References | Pubmed ID | 26305933 |