Vhf00703 details

Gene vhfRNAi AccessionVhf00703
Gene SymbolDYSF
Gene DescriptionDysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1)
Gene Name in PaperDYSF
GroupRestriction Factor
Ensembl Gene IDENST00000258104  ENST00000394120  ENST00000409366  ENST00000409582  ENST00000409651  ENST00000409744  ENST00000409762  ENST00000410020  ENST00000410041  ENST00000413539  ENST00000429174  
UniProt IDO75923
Entrez Gene ID8291
GOView
Host OrganismHomo sapiens
Virus Virus full nameAdeno-associated virus
Virus AbbreviationAAV 
TaxonomyView
Results PhenotypeInhibited transduction
Hits Number*1483
Confirmed Hits Number968 
ScoreNA
UnitNA
Methods Assay Type cell-based
BioModel DescriptionHEK293 and HeLa cells
Confirmatory Screen DescriptionImmunofluorescence
Primary Screen Description#log 2 Luc/AB ratio >2
Note/CommentHost restriction factors critical for in vivo AAV transduction
References Pubmed ID26305933
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)