Vhf00698 details

Gene vhfRNAi AccessionVhf00698
Gene SymbolSYNPO
Gene DescriptionSynaptopodin
Gene Name in PaperSYNPO
GroupRestriction Factor
Ensembl Gene IDENST00000307662  ENST00000394243  ENST00000519664  ENST00000522122  
UniProt IDQ8N3V7
Entrez Gene ID11346
GOView
Host OrganismHomo sapiens
Virus Virus full nameAdeno-associated virus
Virus AbbreviationAAV 
TaxonomyView
Results PhenotypeInhibited transduction
Hits Number*1483
Confirmed Hits Number968 
ScoreNA
UnitNA
Methods Assay Type cell-based
BioModel DescriptionHEK293 and HeLa cells
Confirmatory Screen DescriptionImmunofluorescence
Primary Screen Description#log 2 Luc/AB ratio >2
Note/CommentHost restriction factors critical for in vivo AAV transduction
References Pubmed ID26305933
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)