RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf00634 |
| Gene Symbol | DC1I2 | |
| Gene Description | Cytoplasmic dynein 1 intermediate chain 2 (Cytoplasmic dynein intermediate chain 2) (Dynein intermediate chain 2, cytosolic) (DH IC-2) | |
| Gene Name in Paper | DNCI2 | |
| Group | Restriction Factor | |
| Ensembl Gene ID | ENST00000340296 ENST00000397119 ENST00000409197 ENST00000409317 ENST00000409453 ENST00000409773 ENST00000410079 ENST00000508530 | |
| UniProt ID | Q13409 | |
| Entrez Gene ID | 1781 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Adeno-associated virus |
| Virus Abbreviation | AAV | |
| Taxonomy | View | |
| Results | Phenotype | Inhibited transduction |
| Hits Number* | 1483 | |
| Confirmed Hits Number | 968 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | cell-based |
| BioModel Description | HEK293 and HeLa cells | |
| Confirmatory Screen Description | Immunofluorescence | |
| Primary Screen Description# | log 2 Luc/AB ratio >2 | |
| Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
| References | Pubmed ID | 26305933 |