Vhf00632 details

Gene vhfRNAi AccessionVhf00632
Gene SymbolTAGL3
Gene DescriptionTransgelin-3 (Neuronal protein 22) (NP22) (Neuronal protein NP25)
Gene Name in PaperNP25
GroupRestriction Factor
Ensembl Gene IDENST00000273368  ENST00000393917  ENST00000455401  ENST00000478951  
UniProt IDQ9UI15
Entrez Gene ID29114
GOView
Host OrganismHomo sapiens
Virus Virus full nameAdeno-associated virus
Virus AbbreviationAAV 
TaxonomyView
Results PhenotypeInhibited transduction
Hits Number*1483
Confirmed Hits Number968 
ScoreNA
UnitNA
Methods Assay Type cell-based
BioModel DescriptionHEK293 and HeLa cells
Confirmatory Screen DescriptionImmunofluorescence
Primary Screen Description#log 2 Luc/AB ratio >2
Note/CommentHost restriction factors critical for in vivo AAV transduction
References Pubmed ID26305933
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)