RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf00566 |
| Gene Symbol | C11B1 | |
| Gene Description | Cytochrome P450 11B1, mitochondrial (CYPXIB1) (Cytochrome P-450c11) (Cytochrome P450C11) (Steroid 11-beta-hydroxylase) (EC 1.14.15.4) | |
| Gene Name in Paper | CYP11B1 | |
| Group | Restriction Factor | |
| Ensembl Gene ID | ENST00000292427 ENST00000517471 | |
| UniProt ID | P15538 | |
| Entrez Gene ID | 1584 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Adeno-associated virus |
| Virus Abbreviation | AAV | |
| Taxonomy | View | |
| Results | Phenotype | Inhibited transduction |
| Hits Number* | 1483 | |
| Confirmed Hits Number | 968 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | cell-based |
| BioModel Description | HEK293 and HeLa cells | |
| Confirmatory Screen Description | Immunofluorescence | |
| Primary Screen Description# | log 2 Luc/AB ratio >2 | |
| Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
| References | Pubmed ID | 26305933 |