Vhf00557 details

Gene vhfRNAi AccessionVhf00557
Gene SymbolCENPE
Gene DescriptionCentromere-associated protein E (Centromere protein E) (CENP-E) (Kinesin-related protein CENPE)
Gene Name in PaperCENPE
GroupRestriction Factor
Ensembl Gene IDENST00000265148  ENST00000380026  
UniProt IDQ02224
Entrez Gene ID1062
GOView
Host OrganismHomo sapiens
Virus Virus full nameAdeno-associated virus
Virus AbbreviationAAV 
TaxonomyView
Results PhenotypeInhibited transduction
Hits Number*1483
Confirmed Hits Number968 
ScoreNA
UnitNA
Methods Assay Type cell-based
BioModel DescriptionHEK293 and HeLa cells
Confirmatory Screen DescriptionImmunofluorescence
Primary Screen Description#log 2 Luc/AB ratio >2
Note/CommentHost restriction factors critical for in vivo AAV transduction
References Pubmed ID26305933
_________________

*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)