RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf00549 |
| Gene Symbol | OPRM | |
| Gene Description | Mu-type opioid receptor (M-OR-1) (MOR-1) (Mu opiate receptor) (Mu opioid receptor) (MOP) (hMOP) | |
| Gene Name in Paper | OPRM1 | |
| Group | Restriction Factor | |
| Ensembl Gene ID | ENST00000229768 ENST00000330432 ENST00000337049 ENST00000414028 ENST00000419506 ENST00000428397 ENST00000434900 ENST00000435918 ENST00000452687 ENST00000518759 ENST00000519083 ENST00000520708 ENST00000522236 ENST00000522555 ENST00000522739 ENST00000524150 ENST00000524163 | |
| UniProt ID | P35372 | |
| Entrez Gene ID | 4988 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Adeno-associated virus |
| Virus Abbreviation | AAV | |
| Taxonomy | View | |
| Results | Phenotype | Inhibited transduction |
| Hits Number* | 1483 | |
| Confirmed Hits Number | 968 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | cell-based |
| BioModel Description | HEK293 and HeLa cells | |
| Confirmatory Screen Description | Immunofluorescence | |
| Primary Screen Description# | log 2 Luc/AB ratio >2 | |
| Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
| References | Pubmed ID | 26305933 |