RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf00542 |
| Gene Symbol | LYZL5 | |
| Gene Description | Sperm acrosome-associated protein 5 (EC 3.2.1.17) (Lysozyme-like protein 5) (Sperm-specific lysozyme-like protein X) (SLLP-X) | |
| Gene Name in Paper | LOC389852 | |
| Group | Restriction Factor | |
| Ensembl Gene ID | ENST00000304270 ENST00000304355 ENST00000376940 | |
| UniProt ID | Q96QH8 | |
| Entrez Gene ID | 389852 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Adeno-associated virus |
| Virus Abbreviation | AAV | |
| Taxonomy | View | |
| Results | Phenotype | Inhibited transduction |
| Hits Number* | 1483 | |
| Confirmed Hits Number | 968 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | cell-based |
| BioModel Description | HEK293 and HeLa cells | |
| Confirmatory Screen Description | Immunofluorescence | |
| Primary Screen Description# | log 2 Luc/AB ratio >2 | |
| Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
| References | Pubmed ID | 26305933 |