Vhf00530 details

Gene vhfRNAi AccessionVhf00530
Gene SymbolTBCEL
Gene DescriptionTubulin-specific chaperone cofactor E-like protein (EL) (Leucine-rich repeat-containing protein 35)
Gene Name in PaperMGC10233
GroupRestriction Factor
Ensembl Gene IDENST00000422003  ENST00000529397  
UniProt IDQ5QJ74
Entrez Gene ID219899
GOView
Host OrganismHomo sapiens
Virus Virus full nameAdeno-associated virus
Virus AbbreviationAAV 
TaxonomyView
Results PhenotypeInhibited transduction
Hits Number*1483
Confirmed Hits Number968 
ScoreNA
UnitNA
Methods Assay Type cell-based
BioModel DescriptionHEK293 and HeLa cells
Confirmatory Screen DescriptionImmunofluorescence
Primary Screen Description#log 2 Luc/AB ratio >2
Note/CommentHost restriction factors critical for in vivo AAV transduction
References Pubmed ID26305933
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)