RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf00528 |
| Gene Symbol | CCL14 | |
| Gene Description | C-C motif chemokine 14 (Chemokine CC-1/CC-3) (HCC-1/HCC-3) (HCC-1(1-74)) (NCC-2) (Small-inducible cytokine A14) [Cleaved into: HCC-1(3-74); HCC-1(4-74); HCC-1(9-74)] | |
| Gene Name in Paper | CCL14 | |
| Group | Restriction Factor | |
| Ensembl Gene ID | ENST00000618404 ENST00000619040 ENST00000622526 ENST00000632700 | |
| UniProt ID | Q16627 | |
| Entrez Gene ID | 6358 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Adeno-associated virus |
| Virus Abbreviation | AAV | |
| Taxonomy | View | |
| Results | Phenotype | Inhibited transduction |
| Hits Number* | 1483 | |
| Confirmed Hits Number | 968 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | cell-based |
| BioModel Description | HEK293 and HeLa cells | |
| Confirmatory Screen Description | Immunofluorescence | |
| Primary Screen Description# | log 2 Luc/AB ratio >2 | |
| Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
| References | Pubmed ID | 26305933 |