Vhf00514 details

Gene vhfRNAi AccessionVhf00514
Gene SymbolFYCO1
Gene DescriptionFYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7)
Gene Name in PaperFYCO1
GroupRestriction Factor
Ensembl Gene IDENST00000296137  ENST00000535325  
UniProt IDQ9BQS8
Entrez Gene ID79443
GOView
Host OrganismHomo sapiens
Virus Virus full nameAdeno-associated virus
Virus AbbreviationAAV 
TaxonomyView
Results PhenotypeInhibited transduction
Hits Number*1483
Confirmed Hits Number968 
ScoreNA
UnitNA
Methods Assay Type cell-based
BioModel DescriptionHEK293 and HeLa cells
Confirmatory Screen DescriptionImmunofluorescence
Primary Screen Description#log 2 Luc/AB ratio >2
Note/CommentHost restriction factors critical for in vivo AAV transduction
References Pubmed ID26305933
_________________

*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)