Vhf00485 details

Gene vhfRNAi AccessionVhf00485
Gene SymbolARHGQ
Gene DescriptionRho guanine nucleotide exchange factor 26 (SH3 domain-containing guanine exchange factor)
Gene Name in PaperSGEF
GroupRestriction Factor
Ensembl Gene IDENST00000356448  ENST00000465093  ENST00000465817  ENST00000496710  ENST00000614308  ENST00000618535  ENST00000629129  ENST00000630729  
UniProt IDQ96DR7
Entrez Gene ID26084
GOView
Host OrganismHomo sapiens
Virus Virus full nameAdeno-associated virus
Virus AbbreviationAAV 
TaxonomyView
Results PhenotypeInhibited transduction
Hits Number*1483
Confirmed Hits Number968 
ScoreNA
UnitNA
Methods Assay Type cell-based
BioModel DescriptionHEK293 and HeLa cells
Confirmatory Screen DescriptionImmunofluorescence
Primary Screen Description#log 2 Luc/AB ratio >2
Note/CommentHost restriction factors critical for in vivo AAV transduction
References Pubmed ID26305933
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)