RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf00461 |
| Gene Symbol | NFIC | |
| Gene Description | Nuclear factor 1 C-type (NF1-C) (Nuclear factor 1/C) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/C) (NF-I/C) (NFI-C) (TGGCA-binding protein) | |
| Gene Name in Paper | NFIC | |
| Group | Restriction Factor | |
| Ensembl Gene ID | ENST00000341919 ENST00000395111 ENST00000443272 ENST00000586919 ENST00000589123 ENST00000590282 | |
| UniProt ID | P08651 | |
| Entrez Gene ID | 4782 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Adeno-associated virus |
| Virus Abbreviation | AAV | |
| Taxonomy | View | |
| Results | Phenotype | Inhibited transduction |
| Hits Number* | 1483 | |
| Confirmed Hits Number | 968 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | cell-based |
| BioModel Description | HEK293 and HeLa cells | |
| Confirmatory Screen Description | Immunofluorescence | |
| Primary Screen Description# | log 2 Luc/AB ratio >2 | |
| Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
| References | Pubmed ID | 26305933 |