Vhf00459 details

Gene vhfRNAi AccessionVhf00459
Gene SymbolBOC
Gene DescriptionBrother of CDO (Protein BOC)
Gene Name in PaperBOC
GroupRestriction Factor
Ensembl Gene IDENST00000273395  ENST00000355385  ENST00000495514  
UniProt IDQ9BWV1
Entrez Gene ID91653
GOView
Host OrganismHomo sapiens
Virus Virus full nameAdeno-associated virus
Virus AbbreviationAAV 
TaxonomyView
Results PhenotypeInhibited transduction
Hits Number*1483
Confirmed Hits Number968 
ScoreNA
UnitNA
Methods Assay Type cell-based
BioModel DescriptionHEK293 and HeLa cells
Confirmatory Screen DescriptionImmunofluorescence
Primary Screen Description#log 2 Luc/AB ratio >2
Note/CommentHost restriction factors critical for in vivo AAV transduction
References Pubmed ID26305933
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)