Vhf00434 details

Gene vhfRNAi AccessionVhf00434
Gene SymbolSV2B
Gene DescriptionSynaptic vesicle glycoprotein 2B
Gene Name in PaperSV2B
GroupRestriction Factor
Ensembl Gene IDENST00000330276  ENST00000394232  ENST00000545111  ENST00000557410  
UniProt IDQ7L1I2
Entrez Gene ID9899
GOView
Host OrganismHomo sapiens
Virus Virus full nameAdeno-associated virus
Virus AbbreviationAAV 
TaxonomyView
Results PhenotypeInhibited transduction
Hits Number*1483
Confirmed Hits Number968 
ScoreNA
UnitNA
Methods Assay Type cell-based
BioModel DescriptionHEK293 and HeLa cells
Confirmatory Screen DescriptionImmunofluorescence
Primary Screen Description#log 2 Luc/AB ratio >2
Note/CommentHost restriction factors critical for in vivo AAV transduction
References Pubmed ID26305933
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)