RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf00405 |
| Gene Symbol | PTN20 | |
| Gene Description | Tyrosine-protein phosphatase non-receptor type 20 (hPTPN20) (EC 3.1.3.48) | |
| Gene Name in Paper | DKFZP566K0524 | |
| Group | Restriction Factor | |
| Ensembl Gene ID | ENST00000374218 ENST00000374339 ENST00000374346 ENST00000395721 ENST00000395725 ENST00000395727 ENST00000502254 ENST00000502705 ENST00000503851 ENST00000505814 ENST00000506080 ENST00000508602 ENST00000509599 ENST00000509774 ENST00000509900 ENST00000510335 ENST00000511769 ENST00000513156 ENST00000513266 | |
| UniProt ID | Q4JDL3 | |
| Entrez Gene ID | 26095 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Adeno-associated virus |
| Virus Abbreviation | AAV | |
| Taxonomy | View | |
| Results | Phenotype | Inhibited transduction |
| Hits Number* | 1483 | |
| Confirmed Hits Number | 968 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | cell-based |
| BioModel Description | HEK293 and HeLa cells | |
| Confirmatory Screen Description | Immunofluorescence | |
| Primary Screen Description# | log 2 Luc/AB ratio >2 | |
| Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
| References | Pubmed ID | 26305933 |