Vhf00390 details

Gene vhfRNAi AccessionVhf00390
Gene SymbolCQ053
Gene DescriptionUncharacterized protein C17orf53
Gene Name in PaperMGC3130
GroupRestriction Factor
Ensembl Gene IDENST00000245382  ENST00000319977  ENST00000585683  
UniProt IDQ8N3J3
Entrez Gene ID78995
GOView
Host OrganismHomo sapiens
Virus Virus full nameAdeno-associated virus
Virus AbbreviationAAV 
TaxonomyView
Results PhenotypeInhibited transduction
Hits Number*1483
Confirmed Hits Number968 
ScoreNA
UnitNA
Methods Assay Type cell-based
BioModel DescriptionHEK293 and HeLa cells
Confirmatory Screen DescriptionImmunofluorescence
Primary Screen Description#log 2 Luc/AB ratio >2
Note/CommentHost restriction factors critical for in vivo AAV transduction
References Pubmed ID26305933
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)