RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf00385 |
Gene Symbol | MYL1 | |
Gene Description | Myosin light chain 1/3, skeletal muscle isoform (MLC1/MLC3) (MLC1F/MLC3F) (Myosin light chain alkali 1/2) (Myosin light chain A1/A2) | |
Gene Name in Paper | MYL1 | |
Group | Restriction Factor | |
Ensembl Gene ID | ENST00000341685 ENST00000352451 | |
UniProt ID | P05976 | |
Entrez Gene ID | 4632 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Adeno-associated virus |
Virus Abbreviation | AAV | |
Taxonomy | View | |
Results | Phenotype | Inhibited transduction |
Hits Number* | 1483 | |
Confirmed Hits Number | 968 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | cell-based |
BioModel Description | HEK293 and HeLa cells | |
Confirmatory Screen Description | Immunofluorescence | |
Primary Screen Description# | log 2 Luc/AB ratio >2 | |
Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
References | Pubmed ID | 26305933 |