RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf00370 |
| Gene Symbol | H4 | |
| Gene Description | Histone H4 | |
| Gene Name in Paper | HIST1H4D | |
| Group | Restriction Factor | |
| Ensembl Gene ID | ENST00000244537 ENST00000355057 ENST00000358064 ENST00000377727 ENST00000377745 ENST00000377803 ENST00000539745 ENST00000578186 ENST00000579512 ENST00000611927 ENST00000612061 ENST00000613412 ENST00000614247 ENST00000614272 ENST00000615164 ENST00000615353 ENST00000617569 ENST00000618193 ENST00000618305 ENST00000621520 ENST00000634560 ENST00000634956 ENST00000635491 | |
| UniProt ID | P62805 | |
| Entrez Gene ID | 121504;554313;8294;8359;8360;8361;8362;8363;8364;8365;8366;8367;8368;8370 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Adeno-associated virus |
| Virus Abbreviation | AAV | |
| Taxonomy | View | |
| Results | Phenotype | Inhibited transduction |
| Hits Number* | 1483 | |
| Confirmed Hits Number | 968 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | cell-based |
| BioModel Description | HEK293 and HeLa cells | |
| Confirmatory Screen Description | Immunofluorescence | |
| Primary Screen Description# | log 2 Luc/AB ratio >2 | |
| Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
| References | Pubmed ID | 26305933 |