Vhf00365 details

Gene vhfRNAi AccessionVhf00365
Gene SymbolDOCK9
Gene DescriptionDedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin-1)
Gene Name in PaperDOCK9
GroupRestriction Factor
Ensembl Gene IDENST00000376460  ENST00000627024  
UniProt IDQ9BZ29
Entrez Gene ID23348
GOView
Host OrganismHomo sapiens
Virus Virus full nameAdeno-associated virus
Virus AbbreviationAAV 
TaxonomyView
Results PhenotypeInhibited transduction
Hits Number*1483
Confirmed Hits Number968 
ScoreNA
UnitNA
Methods Assay Type cell-based
BioModel DescriptionHEK293 and HeLa cells
Confirmatory Screen DescriptionImmunofluorescence
Primary Screen Description#log 2 Luc/AB ratio >2
Note/CommentHost restriction factors critical for in vivo AAV transduction
References Pubmed ID26305933
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)