RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf00329 |
| Gene Symbol | KRT81 | |
| Gene Description | Keratin, type II cuticular Hb1 (Hair keratin K2.9) (Keratin, hair, basic, 1) (Keratin-81) (K81) (Metastatic lymph node 137 gene protein) (MLN 137) (Type II hair keratin Hb1) (Type-II keratin Kb21) (ghHKb1) (ghHb1) | |
| Gene Name in Paper | KRTHB1 | |
| Group | Restriction Factor | |
| Ensembl Gene ID | ENST00000327741 | |
| UniProt ID | Q14533 | |
| Entrez Gene ID | 3887 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Adeno-associated virus |
| Virus Abbreviation | AAV | |
| Taxonomy | View | |
| Results | Phenotype | Inhibited transduction |
| Hits Number* | 1483 | |
| Confirmed Hits Number | 968 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | cell-based |
| BioModel Description | HEK293 and HeLa cells | |
| Confirmatory Screen Description | Immunofluorescence | |
| Primary Screen Description# | log 2 Luc/AB ratio >2 | |
| Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
| References | Pubmed ID | 26305933 |