RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf00322 |
Gene Symbol | S14L1 | |
Gene Description | SEC14-like protein 1 | |
Gene Name in Paper | SEC14L1 | |
Group | Restriction Factor | |
Ensembl Gene ID | ENST00000392476 ENST00000430767 ENST00000431431 ENST00000436233 ENST00000443798 ENST00000585618 ENST00000591437 | |
UniProt ID | Q92503 | |
Entrez Gene ID | 6397 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Adeno-associated virus |
Virus Abbreviation | AAV | |
Taxonomy | View | |
Results | Phenotype | Inhibited transduction |
Hits Number* | 1483 | |
Confirmed Hits Number | 968 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | cell-based |
BioModel Description | HEK293 and HeLa cells | |
Confirmatory Screen Description | Immunofluorescence | |
Primary Screen Description# | log 2 Luc/AB ratio >2 | |
Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
References | Pubmed ID | 26305933 |