RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf00312 |
| Gene Symbol | CTCFL | |
| Gene Description | Transcriptional repressor CTCFL (Brother of the regulator of imprinted sites) (CCCTC-binding factor) (CTCF paralog) (CTCF-like protein) (Cancer/testis antigen 27) (CT27) (Zinc finger protein CTCF-T) | |
| Gene Name in Paper | CTCFL | |
| Group | Restriction Factor | |
| Ensembl Gene ID | ENST00000243914 ENST00000371196 ENST00000422109 ENST00000422869 ENST00000423479 ENST00000429804 ENST00000432255 ENST00000433949 ENST00000502686 ENST00000539382 ENST00000608263 ENST00000608440 ENST00000608903 ENST00000609232 | |
| UniProt ID | Q8NI51 | |
| Entrez Gene ID | 140690 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Adeno-associated virus |
| Virus Abbreviation | AAV | |
| Taxonomy | View | |
| Results | Phenotype | Inhibited transduction |
| Hits Number* | 1483 | |
| Confirmed Hits Number | 968 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | cell-based |
| BioModel Description | HEK293 and HeLa cells | |
| Confirmatory Screen Description | Immunofluorescence | |
| Primary Screen Description# | log 2 Luc/AB ratio >2 | |
| Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
| References | Pubmed ID | 26305933 |