RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf00303 |
| Gene Symbol | TKN4 | |
| Gene Description | Tachykinin-4 (Preprotachykinin-C) (PPT-C) [Cleaved into: Endokinin-A (EKA); Endokinin-A/B (EKA/B); Endokinin-C (EKC)] | |
| Gene Name in Paper | TAC4 | |
| Group | Restriction Factor | |
| Ensembl Gene ID | ENST00000326219 ENST00000334568 ENST00000352793 ENST00000398154 ENST00000436235 | |
| UniProt ID | Q86UU9 | |
| Entrez Gene ID | 255061 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Adeno-associated virus |
| Virus Abbreviation | AAV | |
| Taxonomy | View | |
| Results | Phenotype | Inhibited transduction |
| Hits Number* | 1483 | |
| Confirmed Hits Number | 968 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | cell-based |
| BioModel Description | HEK293 and HeLa cells | |
| Confirmatory Screen Description | Immunofluorescence | |
| Primary Screen Description# | log 2 Luc/AB ratio >2 | |
| Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
| References | Pubmed ID | 26305933 |