Vhf00291 details

Gene vhfRNAi AccessionVhf00291
Gene SymbolIPRI
Gene DescriptionInositol 1,4,5-trisphosphate receptor-interacting protein (Protein DANGER)
Gene Name in PaperKIAA1754
GroupRestriction Factor
Ensembl Gene IDENST00000278071  ENST00000337478  ENST00000358187  
UniProt IDQ8IWB1
Entrez Gene ID85450
GOView
Host OrganismHomo sapiens
Virus Virus full nameAdeno-associated virus
Virus AbbreviationAAV 
TaxonomyView
Results PhenotypeInhibited transduction
Hits Number*1483
Confirmed Hits Number968 
ScoreNA
UnitNA
Methods Assay Type cell-based
BioModel DescriptionHEK293 and HeLa cells
Confirmatory Screen DescriptionImmunofluorescence
Primary Screen Description#log 2 Luc/AB ratio >2
Note/CommentHost restriction factors critical for in vivo AAV transduction
References Pubmed ID26305933
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)