RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf00254 |
| Gene Symbol | LIMS1 | |
| Gene Description | LIM and senescent cell antigen-like-containing domain protein 1 (Particularly interesting new Cys-His protein 1) (PINCH-1) (Renal carcinoma antigen NY-REN-48) | |
| Gene Name in Paper | LIMS1 | |
| Group | Restriction Factor | |
| Ensembl Gene ID | ENST00000332345 ENST00000338045 ENST00000393310 ENST00000409441 ENST00000410093 ENST00000544547 | |
| UniProt ID | P48059 | |
| Entrez Gene ID | 3987 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Adeno-associated virus |
| Virus Abbreviation | AAV | |
| Taxonomy | View | |
| Results | Phenotype | Inhibited transduction |
| Hits Number* | 1483 | |
| Confirmed Hits Number | 968 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | cell-based |
| BioModel Description | HEK293 and HeLa cells | |
| Confirmatory Screen Description | Immunofluorescence | |
| Primary Screen Description# | log 2 Luc/AB ratio >2 | |
| Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
| References | Pubmed ID | 26305933 |