RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf00241 |
| Gene Symbol | DEFI8 | |
| Gene Description | Differentially expressed in FDCP 8 homolog (DEF-8) | |
| Gene Name in Paper | FLJ20186 | |
| Group | Restriction Factor | |
| Ensembl Gene ID | ENST00000268676 ENST00000418391 ENST00000563594 ENST00000563795 ENST00000567874 ENST00000569453 ENST00000570182 ENST00000610455 ENST00000617948 | |
| UniProt ID | Q6ZN54 | |
| Entrez Gene ID | 54849 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Adeno-associated virus |
| Virus Abbreviation | AAV | |
| Taxonomy | View | |
| Results | Phenotype | Inhibited transduction |
| Hits Number* | 1483 | |
| Confirmed Hits Number | 968 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | cell-based |
| BioModel Description | HEK293 and HeLa cells | |
| Confirmatory Screen Description | Immunofluorescence | |
| Primary Screen Description# | log 2 Luc/AB ratio >2 | |
| Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
| References | Pubmed ID | 26305933 |