RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf00199 |
Gene Symbol | PARPT | |
Gene Description | TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 14) (ARTD14) (Poly [ADP-ribose] polymerase 7) (PARP-7) | |
Gene Name in Paper | TIPARP | |
Group | Restriction Factor | |
Ensembl Gene ID | ENST00000295924 ENST00000461166 ENST00000486483 ENST00000542783 | |
UniProt ID | Q7Z3E1 | |
Entrez Gene ID | 25976 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Adeno-associated virus |
Virus Abbreviation | AAV | |
Taxonomy | View | |
Results | Phenotype | Inhibited transduction |
Hits Number* | 1483 | |
Confirmed Hits Number | 968 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | cell-based |
BioModel Description | HEK293 and HeLa cells | |
Confirmatory Screen Description | Immunofluorescence | |
Primary Screen Description# | log 2 Luc/AB ratio >2 | |
Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
References | Pubmed ID | 26305933 |