RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf00191 |
Gene Symbol | ARI5B | |
Gene Description | AT-rich interactive domain-containing protein 5B (ARID domain-containing protein 5B) (MRF1-like protein) (Modulator recognition factor 2) (MRF-2) | |
Gene Name in Paper | ARID5B | |
Group | Restriction Factor | |
Ensembl Gene ID | ENST00000279873 ENST00000309334 | |
UniProt ID | Q14865 | |
Entrez Gene ID | 84159 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Adeno-associated virus |
Virus Abbreviation | AAV | |
Taxonomy | View | |
Results | Phenotype | Inhibited transduction |
Hits Number* | 1483 | |
Confirmed Hits Number | 968 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | cell-based |
BioModel Description | HEK293 and HeLa cells | |
Confirmatory Screen Description | Immunofluorescence | |
Primary Screen Description# | log 2 Luc/AB ratio >2 | |
Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
References | Pubmed ID | 26305933 |