Vhf00166 details

Gene vhfRNAi AccessionVhf00166
Gene SymbolCIRBP
Gene DescriptionCold-inducible RNA-binding protein (A18 hnRNP) (Glycine-rich RNA-binding protein CIRP)
Gene Name in PaperCIRBP
GroupRestriction Factor
Ensembl Gene IDENST00000320936  ENST00000413636  ENST00000585630  ENST00000586472  ENST00000588030  ENST00000588090  
UniProt IDQ14011
Entrez Gene ID1153
GOView
Host OrganismHomo sapiens
Virus Virus full nameAdeno-associated virus
Virus AbbreviationAAV 
TaxonomyView
Results PhenotypeInhibited transduction
Hits Number*1483
Confirmed Hits Number968 
ScoreNA
UnitNA
Methods Assay Type cell-based
BioModel DescriptionHEK293 and HeLa cells
Confirmatory Screen DescriptionImmunofluorescence
Primary Screen Description#log 2 Luc/AB ratio >2
Note/CommentHost restriction factors critical for in vivo AAV transduction
References Pubmed ID26305933
_________________

*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)