RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf00135 |
Gene Symbol | IL3RB | |
Gene Description | Cytokine receptor common subunit beta (CDw131) (GM-CSF/IL-3/IL-5 receptor common beta subunit) (CD antigen CD131) | |
Gene Name in Paper | CSF2RB | |
Group | Restriction Factor | |
Ensembl Gene ID | ENST00000403662 ENST00000406230 | |
UniProt ID | P32927 | |
Entrez Gene ID | 1439 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Adeno-associated virus |
Virus Abbreviation | AAV | |
Taxonomy | View | |
Results | Phenotype | Inhibited transduction |
Hits Number* | 1483 | |
Confirmed Hits Number | 968 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | cell-based |
BioModel Description | HEK293 and HeLa cells | |
Confirmatory Screen Description | Immunofluorescence | |
Primary Screen Description# | log 2 Luc/AB ratio >2 | |
Note/Comment | Host restriction factors critical for in vivo AAV transduction | |
References | Pubmed ID | 26305933 |